VitalMatrix
Evidence-based · 16 supplements · 19 mapped connections

Supplements, connected by science.

Vital Matrix distills the research on popular supplements — the real benefits, side effects, and dosing — then maps how they work together. Stop guessing about your stack.

Research-linkedEvidence-ratedInteraction-aware

Drag a node. Hover to trace its connections.

How it works

From research to a smarter routine

Three layers of clarity, so you understand not just what a supplement does, but how it fits with everything else.

01

Read the evidence

Every supplement is broken down into benefits, side effects, dosing, and a research summary with an evidence rating — no hype, no fluff.

02

See the connections

Supplements never act alone. The matrix maps how they synergize, enhance each other's absorption, or compete — so you can stack smarter.

03

Build your stack

Follow the connections from any supplement to discover what pairs well, what to separate, and what to take with care.

The Matrix

Pairings worth knowing

A few of the best-established supplement relationships — the kind that make a stack greater than the sum of its parts.

Synergy

K2 directs the calcium that D3 helps absorb into bone rather than soft tissue and arteries.

Synergy

The classic nootropic stack: L-theanine smooths caffeine's jitters while preserving the focus boost.

Boosts absorption

Piperine from black pepper can increase curcumin bioavailability dramatically (studies report up to ~20x).

Boosts absorption

Taken together, vitamin C can multiply the absorption of plant-based iron.

Cofactor

Magnesium is required to convert vitamin D into its active form, so low magnesium blunts D3's benefits.

Use with care

Long-term high-dose zinc depletes copper — supplement copper (≈1 mg per 10–15 mg zinc) if using chronically.

Most connected

Start with the hubs

The supplements with the most relationships — often the best foundations for a thoughtful routine.

View all

Map your supplement stack with confidence

Dive into the interactive matrix to see how everything in your routine connects — and where it could work harder for you.